Introduction Periodontal diseases represent one of the most prevalent chronic inflammatory conditions affecting human populations worldwide, characterized by progressive destruction of the tooth-supporting apparatus including gingiva, periodontal ligament, cementum, and alveolar bone. The accurate diagnosis and effective management of these conditions have traditionally relied upon a combination of clinical examination using periodontal probes and radiographic…
Read MoreIntroduction Alveolar bone loss is the defining hallmark of periodontitis, representing the irreversible destruction of the tooth’s supporting structures. The pattern of this bone loss is not random; it is a direct consequence of the spread of inflammation from the gingival margin, modulated by local anatomical factors, host response, and the duration of disease. Recognizing…
Read MoreIntroduction The periodontium, a complex and highly specialized system of tissues, is designed to anchor the tooth within the alveolar bone and withstand the myriad forces of mastication, parafunction, and even speech. For decades, the relationship between occlusion and the health of this supporting apparatus has been a source of intense clinical scrutiny and academic…
Read MoreIntroduction Periodontal therapy refers to the comprehensive treatment aimed at preventing, managing, and reversing periodontal disease, which affects the supporting structures of the teeth, including the gums, periodontal ligament, and alveolar bone. The primary goal of periodontal therapy is to halt the progression of disease, prevent tooth loss, and restore the health and function of…
Read MoreIntroduction Animal models play a crucial role in biomedical research by providing insights into the complex biological processes that occur in humans. In fields like periodontics, where research focuses on understanding disease mechanisms, tissue regeneration, and the efficacy of treatments, animal models are invaluable. They bridge the gap between in vitro studies (experiments in controlled…
Read MoreIntroduction LIGHT protein (Lymphotoxin-beta receptor Interacting with G Protein-coupled Receptor), is a significant cytokine involved in immune regulation and inflammation. It plays a critical role in various physiological and pathological processes, particularly those related to immune responses and inflammation. Understanding LIGHT’s structure, function, and interactions is crucial for grasping its role in diseases, including periodontal…
Read MoreIntroduction As discussed in COVID-19 and dental practice Part-I, COVID-19, caused by the novel coronavirus SARS-CoV-2, first emerged in December 2019 in Wuhan, China. It rapidly evolved from a localized outbreak into a global pandemic, leading to unprecedented challenges for public health systems, economies, and societies worldwide. The World Health Organization (WHO) declared COVID-19 a…
Read MoreIntroduction Who does not know about COVID-19 pandemic? The COVID-19 pandemic, caused by the SARS-CoV-2 virus, has had a profound impact globally since it began in late 2019. As of now, the COVID-19 pandemic has resulted in over 6 million reported deaths worldwide. However, the World Health Organization (WHO) estimates that the actual death toll,…
Read MoreIntroduction Periodontics is a branch of dentistry that focuses on the structures supporting the teeth, including the gums and bone. Traditionally, periodontal treatment has followed a one-size-fits-all approach, often leading to suboptimal outcomes for patients with unique needs. With the advent of personalized medicine, a new paradigm in healthcare, dentistry is poised to revolutionize the…
Read MoreIntroduction Periodontal diseases, including gingivitis and periodontitis, can lead to the destruction of these supporting structures, ultimately resulting in tooth loss if not adequately treated. Various biomaterials have been used so far for periodontal regeneration purposes. Recent advances in biomaterials and regenerative techniques have introduced nanografts as a promising approach to periodontal regeneration. This comprehensive…
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