Principles of prescription writing

Introduction Prescription writing is a core responsibility of healthcare providers. It involves the issuance of instructions regarding the administration of drugs to treat illnesses or conditions. Despite advances in digital technology, prescriptions remain vital to patient care, acting as a bridge between diagnosis and treatment. The art of writing prescriptions lies in striking the balance…

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Genetic Polymorphism

Introduction Genetic Polymorphism refers to the occurrence of two or more distinct alleles at a particular gene locus within a population’s genetic makeup, where the least common allele has a frequency of at least 1% in the population. These variations can exist in the form of single nucleotide differences, insertions, deletions, or larger structural changes…

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Landmark studies in periodontics and implantology

What is a landmark study? A landmark study is a research investigation that significantly impacts a field of study by introducing novel concepts, providing groundbreaking findings, or validating important theories. These studies are often pivotal in shaping future research, influencing clinical practices, or altering theoretical frameworks. Following are the key characteristics of landmark studies: Innovative…

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Peri-implantitis and its management

Introduction Peri-implantitis is a significant and increasingly recognized complication in the field of implant dentistry. As the global prevalence of dental implants rises, so does the occurrence of peri-implant diseases, with peri-implantitis being the most severe form. Characterized by inflammation in the peri-implant tissues and progressive bone loss around the implant, peri-implantitis poses a serious…

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RNA Interference: Mechanisms, Applications, and Therapeutic Potential

Introduction Ribonucleic acid (RNA) is a crucial molecule involved in various biological roles, primarily in coding, decoding, regulation, and expression of genes. Unlike DNA, which is double-stranded, RNA is typically single-stranded and comes in several forms, each serving different functions within the cell. Types of RNA Messenger RNA (mRNA): Carries genetic information from DNA to…

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Arrestin beta-2 deficiency and periodontal inflammation

Introduction Arrestin beta-2 (ARRB2), one of the four members of the arrestin family, plays a pivotal role in cellular signaling, particularly in the regulation of G-protein-coupled receptors (GPCRs). Arrestins, including ARRB2, are versatile scaffold proteins that modulate various signaling pathways, influencing physiological and pathological processes. Arrestin beta-2 is a multi-domain protein consisting of approximately 410…

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COVID-19 and dental practice Part-II

Introduction As discussed in COVID-19 and dental practice Part-I, COVID-19, caused by the novel coronavirus SARS-CoV-2, first emerged in December 2019 in Wuhan, China. It rapidly evolved from a localized outbreak into a global pandemic, leading to unprecedented challenges for public health systems, economies, and societies worldwide. The World Health Organization (WHO) declared COVID-19 a…

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Artificial intelligence (AI) in periodontal practice and implant dentistry

Introduction Artificial intelligence (AI) has rapidly evolved from a concept of science fiction to a transformative force in various industries, including healthcare. Dentistry, particularly the fields of periodontics and implantology, has seen significant advancements due to the integration of AI technologies. These innovations have the potential to revolutionize diagnostic processes, treatment planning, and patient care,…

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