Role of Porphyromonas gingivalis in pathogenesis of periodontitis

Introduction to Porphyromonas gingivalis (P. gingivalis) P. gingivalis is a Gram-negative, anaerobic, non-motile, asaccharolytic and black pigmented rod that form greenish-black colonies on blood agar plates 137. It is one of the major pathogens of chronic periodontitis 138, 139. This microorganism has been included in the red complex, which is strongly associated with periodontal destruction.…

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Role of Aggregatibacter actinomycetemcomitans in periodontal diseases

Introduction to Aggregatibacter actinomycetemcomitans This bacterium was first isolated by Klinger 81 from a cervicofacial actinomycotic lesion in 1912 and was named Bacterium actinomycetemcomitans. Topley and Wilson (1929) 82 reclassified it as Actinobacillus actinomycetemcomitans and Potts et al. (1985) 83 as Haemophilus actinomycetemcomitans. In 2006 it was again reclassified based on multilocus sequence analysis by…

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Host-microbial interactions in periodontal diseases

Introduction to the host-microbial interactions in periodontal diseases The microbial biofilm that forms around the teeth is the main cause of periodontal disease initiation and progression. This biofilm is a complex community of microorganisms which produces various virulence factors that initiate the inflammatory response. The enzymes released by bacteria in the biofilm include proteases that…

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Dental calculus and its role in etiopathogenesis of periodontal diseases

Introduction to dental calculus Although, dental plaque is considered as the primary etiological factor in the development of periodontal diseases; the presence of dental calculus is also of great concern to the clinicians because it facilitates plaque formation by providing the surface for its formation and keeps it in close contact with the gingival tissue.…

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Alveolar bone

Introduction to alveolar bone Alveolar bone is the specialized part of maxillary and mandibular bone that supports the teeth. It forms with the eruption of teeth and gradually disappears after the tooth is lost. The alveolar bone consists of an outer cortical plate which is composed of Haversian bone and compacted bone lamellae, a central…

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