Application of growth factors in periodontal regeneration

Introduction to growth factors Growth factors are polypeptide molecules released by cells in the inflamed area that regulate events in wound healing. These are naturally occurring proteins that regulate various aspects of cell growth and development, acting locally or systemically. “Growth factor” is a general term to denote a class of polypeptide hormones that stimulate…

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Root surface biomodification

Introduction to root surface biomodification To achieve new attachment on the diseased root surfaces affected by periodontal disease, it is necessary to eliminate calculus, bacterial plaque and other cytotoxic substances on or within the root surface. Periodontitis-affected root surfaces are hypermineralized and contaminated with cytotoxic and other biologically active substances 1. The non-surgical periodontal therapy,…

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Guided bone regeneration

Introduction to guided bone regeneration Periodontal regeneration has been a field of research for quite a long time now. Although, complete periodontal regeneration is still to be achieved; we have succeeded in developing techniques which enhance regeneration. These techniques include root surface biomodification, guided tissue regeneration, application of fibrin-rich, and platelet-rich plasma in periodontal regeneration…

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Guided tissue regeneration

Introduction to guided tissue regeneration The ultimate goal of periodontal therapy is to restore the periodontal health and regeneration of the lost periodontal structures. The conventional non-surgical and surgical periodontal therapies lead to the cessation of the active periodontal disease, but in most cases, they result in repair and not regeneration or new attachment. New…

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History of periodontal regenerative therapy

Introduction With the introduction and advancements in the surgical periodontal pocket therapy, our understanding regarding the type of bone defects and healing following flap surgeries improved dramatically. 1970’s and 80’s may be regarded as two decades when our basic understanding regarding surgical periodontal therapy improved and it was demonstrated that lost periodontal tissue can be…

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Osseous resective surgeries

Introduction to osseous resective surgeries The aim of surgical periodontal pocket therapy is to eliminate or reduce the periodontal pocket depth, achieving a healthy periodontium and creating a periodontal tissue architecture that facilitates the self-performed oral hygiene measures by the patient. The ideal method to treat periodontal pocket and periodontal bony defects is the regeneration…

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